In many countries around the world, people from groups who face discrimination or marginalization, or who have been subject to oppression historically, are facing unique and additional challenges to access Covid-19 vaccines. This is because of insufficient or inadequate consideration of their circumstances, needs and vulnerabilities, and includes women, people of diverse sexual orientations and gender identities, people from Indigenous, descent based and racialised communities. Across the globe, the national and local authorities need to be making much greater efforts to ensure non-discrimination and equality in their vaccine distributions.